Posttraumatic stress disorder (PTSD) is a chronic debilitating dysfunction that may occur due to acute stress in the early aftermath of trauma. Not everyone who experiences a traumatic event will go on to develop acute or chronic dysfunction, lifetime prevalence of PTSD is estimated at around 3.9% worldwide. This syndrome is characterized by four symptom clusters, such as, intrusive thoughts, avoidance of reminders, feeling and thinking negatively, as well as arousal and reactive symptoms. Further biomarker studies found out how these psycho-behavioral abnormalities in immune indicators are jointly among patients. Results have shown higher levels of proinflammatory cytokines, namely, interleukin IL-1β, IL-6, tumour necrosis factor TNF-α, interferon gamma (IFN-ɣ), emphasising how inflammation is one potential dysregulated mechanism in PTSD.