Today, as the Internet Of Things (IoT) world keeps growing, billions of microcontrollers are used as edge devices in a very wide range of applications, from industrial automation to health care dimension. Such massive diffusion of embedded devices in safety-critical and business-critical missions brings up important consequences in terms of security due to hardware and software vulnerabilities of such devices. In literature, many security solutions for microcontrollers have been proposed, relying on both hardware and software techniques. While software-based solutions can be easily evaluated with a proper software toolchain suited for the target ISA, hardware solutions are more critical as they require an open architecture that can be easily customized starting from the core itself.