Graziana Maria Ragonese
In silico mechanical characterization of a new corneal implant for the treatment of keratoconus.
Rel. Diego Gallo, Claudio Chiastra. Politecnico di Torino, Master of science program in Biomedical Engineering, 2022
Abstract
Keratoconus is a progressive degenerative disease that causes the cornea to thin and protrude due to the weakening of the collagen fibers of which it is composed. This could give rise to a significant vision deterioration, potentially leading to blindness if left untreated, and a poor quality of life. Thus the need for new innovative devices to treat keratoconus is arising. The GROSSO® implant is a patented shape memory, Nickel-Titanium (Nitinol) corneal implant to reshape deformed corneas in keratoconus patients. In order to study the mechanical behaviour of the device, ideal 1D and 3D models were developed from 2D designs provided by Recornea (Rhinoceros v.7.0 (Robert McNeel & Associates, Seattle, WA, USA)).
The geometric models were then meshed using beam elements and tetrahedral elements, for 1D and 3D models respectively (Hypermesh 2021 (Altair Engineering, USA))
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