Blood coagulation is a very complex biological process consisting in a strict interplay among several factors which finally results in a delicate thrombohemorrhagic balance. Alterations in the evolution of the coagulation cascade are the primary cause of different dangerous pathological conditions that over the last years interested an ever increasing number of patients. The main treatment consists in the administration of different drug therapies requiring periodic monitoring, therefore, specific tests to assess blood coagulation have been developed, particularly measuring clotting time. Standard laboratory tests are time and resource consuming, both for clinicians and patients, consequently affecting the quality of life. The result is a rising need of a low-cost, fast, and portable device able to perform clotting time tests such as the prothrombin time (PT), the activated partial thromboplastin time (aPTT) and the activated clotting time (ACT).