Chiari malformation (CM) is a rare neurological condition characterized by the herniation of cerebellar tonsils through the foramen magnum. Almost 40-75% of patients with CM develop a syrinx, a fluid-filled cavity inside the spinal cord. The characteristics of the pathology and clinical experience linked the development and resolution of the syrinx to the disrupted fluid dynamics. However, this mechanism has not been fully understood yet. Poroelasticity is a powerful instrument to model porous tissues like the spinal cord. However, only a few studies using this physic to study the CM relate syringomyelia can be found in the literature. Therefore, the objective of this thesis was to investigate the poroelastic behavior of the spinal cord under CM conditions.