Interest in wetting phenomena has significantly increased over the past few decades, both in industry and academia: the existence in nature of biological systems with special wetting properties has led to investigate their potential technological applications, stimulating the creation of bio-inspired surfaces equipped with specific combinations of chemical composition and surface structures. The dynamics of phenomena involving liquid droplets in contact with solid substrates is governed by processes that are still unclear, especially when there are non-smooth or chemically heterogeneous surfaces; many approaches have been developed over the years with the aim of explaining and overcoming some of the unsolved problems, but currently there is no all-encompassing theory.