Marco Cipollini
Using Glauber-Pseudolikelihood Dynamics to Generate Artificial Proteins.
Rel. Andrea Pagnani, Anna Paola Muntoni. Politecnico di Torino, Master of science program in Physics Of Complex Systems, 2021
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Abstract
Since the fundamental processes governing the functioning of the biological cell were first discovered, it became clearer and clearer as research on the subject continued in time that proteins are responsible for a numerous ensemble of different activities which are essential to the survival of all life forms present on this planet. Given this fact, it goes without saying that one of the first issues that biologists and scientists had to deal with was to analyze proteins in order to identify their functions inside the organism. It is well known that proteins are macro-molecules constituted by organic monomers, the amino acids, linked in a chain that eventually, after its assembly in the cell, proceeds to fold into a particular three-dimensional structure, known as the tertiary structure of proteins.
One of the most remarkable discoveries on the subject is that it is indeed this configuration, conveyed by inter-molecular forces between amino acids, that is responsible for the specific role of proteins inside the organism
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