In the current challenge to contain the global warming, renewable energy sources development plays a crucial role to decarbonise the energy sector. In this context, biogas have the potential to act as a renewable energy and carbon source for energy production and chemical industry applications. Biogas production from anaerobic digestion of organic wastes sets allows this renewable energy production in the circular economy frame. Therefore, several EU projects have been and are still conducted. The Waste2Watt project aims at designing flexible cleaning systems to unlock the potentialities of a biogas for CHP production through Fuel Cells. Its focuses are both on small scale applications (e.g.