Swimming is one of the physical activities mainly practiced in the world, with recent improvements to make it easily accessible to people with physical disabilities. However, proper devices for swimmers with limb amputation/deficiency have not been developed yet, mostly due to the ban on their use during competitions. The latter is often remedied using commercial paddles during training, which might limit the swimmer’s performance and cause some injuries due to the unbalanced muscles effort. In last years, a marked interest has emerged on the application of computational fluid dynamics (CFD) to study the flow patterns developing around the swimmer’s body or extremities, with the final aim to provide a numerical estimation of drag and/or lift force acting on the athlete and opposing his/her movements in water.