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Design of a stretchable, conductive silicone-based biomaterial for vocal fold models.
Rel. Gianluca Ciardelli, Irene Carmagnola, Valeria Chiono. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2021
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Abstract
Soft Robotics is based on soft and stretchable organic structures that imitates natural movements and finds widespread use in many biomedical applications: diagnosis, drug delivery, assistive and wearable devices, surgical tools, prostheses or artificial organs. The use of transductors and actuators require that the materials used should also possess adequate electrical conductivity. This thesis originates from the collaboration between Politecnico di Torino (Biomedical Lab) and Scuola Superiore Sant'Anna (Soft Mechatronics for BioRobotics Laboratory of the BioRobotics Lab). The aim of this work is the development of a totally polymeric and conductive material for vocal fold models that satisfies three main requirements: i) stretchability in the physiological range of vocal folds, ii) biocompatibility for potential in vivo applications and iii) electrical conductivity for electroglottography studies as a method of validation of the model.
The proposed strategy involves the blending of a silicone elastomer with poly(3,4-ethylenedioxythiophene:poly(styrene sulfonate) (PEDOT:PSS), with the addition of Triton X-100 as surfactant and Ethylene Glycol as dopant
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