In vitro electroanalytical experiments through multi-electrode arrays (MEAs) are applied to observe the extracellular behaviour of excitable cells and screen the effect of specific chemical modulators and drug injections. MEAs are usually interfaced with an electronic interface consisting of a preamplification stage and a filtering one. In this project, a preamplification stage on a printed circuit board is designed for amplifying a single-channel of the available 16 electrodes of a Micro-Graphitic Single Crystal Diamond Multi-Electrode Array (μG-SCD MEA) chip, realized by the University of Torino. Thus, this read-out device provides essential tools for a future device blending and optimizing the single channel's preamplifier to all the μG-SCD MEA's available electrodes.