This thesis work aims at studying gas sensors based on Layered Double Hydroxides (LDHs), with a focus on the design, testing and optimization of the sensors employed for the detection of Volatile Organic Compounds (VOCs) at room temperature. The LDHs considered show four different compositions, ZnAl-Cl, ZnFe-Cl, ZnAl-NO3, MgAl-NO3, and are tested to varying concentrations of Acetone, Ethanol, Ammonium Hydroxide and Sodium Hypochlorite diluted in dry air. The sensing mechanism involves a variation of the electrical resistance of the sensing material as it is exposed to the analyte to detect.