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Application of Face Recognition methodologies to the classification of proteins

Arian Yousefi Javan

Application of Face Recognition methodologies to the classification of proteins.

Rel. Federica Marcolin, Jacek Adam Tuszynski. Politecnico di Torino, Corso di laurea magistrale in Communications And Computer Networks Engineering (Ingegneria Telematica E Delle Comunicazioni), 2020

Abstract:

Recognition of the possibility for an interaction between two proteins can introduce potential biological functions and may discover novel complexes. In this regard, the first protein can be the Spike of a virus like new discovered and wide-spread Covid-19 disease that usefully may interact with another protein result in eliminating the virus ability to enter the human body. Since the interaction between two proteins based on shape complementarity of their 3D structure, geometrical descriptors of 3D surface that represented for 3D face recognition in computer vision field can reveal the ability of the docking between two proteins. In our protein classification experiment which is based on the docking ability between proteins, we applied four comparison methods on the extracted geometrical features from the proteins surface that can connect each protein with the protein that has the most shape complementary feature. The main aim can be detecting the docking possibility between the Spike proteins of Covid-19 and some of the ACE and Hemoglobin and different Anti-body proteins which can produce novel drugs. The result of our experiment represents that our novel docking recognition can detect potential interaction between the described proteins with different size and resolution by low computational time.

Relators: Federica Marcolin, Jacek Adam Tuszynski
Academic year: 2020/21
Publication type: Electronic
Number of Pages: 123
Additional Information: Tesi secretata. Fulltext non presente
Subjects:
Corso di laurea: Corso di laurea magistrale in Communications And Computer Networks Engineering (Ingegneria Telematica E Delle Comunicazioni)
Classe di laurea: New organization > Master science > LM-27 - TELECOMMUNICATIONS ENGINEERING
Aziende collaboratrici: UNSPECIFIED
URI: http://webthesis.biblio.polito.it/id/eprint/16628
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