Oxygen represents the fuel of life. It is essential for the survival of the entire human organism, from the small cellular compartments to the wide organs. Hence, if absent, it can undermine the physiological behavior of the body. One of the districts that is mainly affected by lack of oxygen is the cardiovascular one where the heart muscle, without O2 supplied by the coronary arteries, hardly contracts and pumps blood to feed the organism. This can occur as a consequence of a coronary heart disease (CHD), namely a myocardial infarction (MI), during which the blood flow headed to the heart is stopped, altering cardiomyocytes functions and eventually leading to their necrosis.