Neural recording in the peripheral nervous system implies to find a balance between selectivity of the recording and invasiveness of the electrodes used. Cuff electrodes consist of cylindrical structures made of an insulating biocompatible material with metal contacts on the inner face, to be placed around the nerve surface. Among the available categories, they are the least invasive and have shown the best long-term implant stability, as they allow to record electroneurograms without compromising the integrity of the nerve structure. However, the identification of the active fibres inside the nerve is extremely complicated if compared with more invasive alternatives, and requires powerful classification algorithms to interpret the signals, achieving selectivity.