Sensor integration and integrated flow control within microfluidic PoC devices Background: This master thesis presents the work and the experiments performed at Micronit micro technologies in the framework of the KardiaTool project. Micronit is a company headquartered in Enschede, Netherlands, specialized in the design, development and production of state-of-the-art devices for microfluidics and MEMS applications. The company offers a wide range of services and products, such as organ-on-chip, microreactors and micromixers design, development, prototyping and manufacturing. The aim of the KardiaTool project is to integrate the concept of saliva biosensing into clinical practicing for addressing the medical needs in personalized heart failure diagnosis and therapy monitoring at point of care.