Nadia Moles
Biomedical nanovectors for the transport of antioxidants of natural origin.
Rel. Valentina Alice Cauda, Gianni Ciofani, Attilio Marino. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2020
Abstract
In recent times, research of natural antioxidants in various fields, such as cosmetics, food treatments and pharmaceuticals, are among the biggest challenges for industry and science. From a biomedical point of view, the strong scavenging power of reactive oxygen species (ROS) makes them functional tools for the treatment of neurodegenerative diseases including Alzheimer's, Parkinson's, Huntington's, Amyotrophic lateral sclerosis, Multiple Sclerosis. Their mechanism of action is based on the reduction of “oxidative stress”, a common characteristic of the above mentioned diseases. Hence, they prove to be a valid alternative to drugs currently used with limited performance. Antioxidants are a very large diversified family of molecules.
Different classifications are reported according to nature (enzymatic or non-enzymatic), chemical-physical properties (hydrophilic or lipophilic) and structure (flavonoids, polyphenols, etc
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