In the last few decades enormous efforts have been made in the nanomedicine researching field. Among the several biomedical applications that nanotechnologies could be applied into, the drug delivery systems based on polymer and/or lipid nanoparticles have shown a great potential for the treatment of a large range of respiratory and tumoral diseases as an alternative of the techniques used nowadays. South Korea is one of the most active countries in this field. A team in the Yonsei University medical research department of Wonju, composed by biologists, chemicals and nanotechnologists, is working to improve the efficacy and the safety of micro-sized polymeric particles as treatment carries for lung-target drugs, focusing in particular to study and synthetize PLGA-based discoidal particles.