Due to the abundance of water resources in Argentina, several dams were built such as the San Roque dam. This thesis analyzes and provides tools for the correct and efficient management of water resources applied to San Roque multipurpose reservoir, which plays an important role in water supply to more than one million and a half inhabitants, in the generation of hydroelectric power, together with irrigation and flood control. Simulation and optimization models were applied using different software, which help to investigate and manipulate the management of the reservoir as well as they can serve in the future for different purposes.