The presented thesis work can be divided into two parts: in the first part the Coronary Artery Simulator of BDC Labs is characterized together with PD-0500 Pump and PD-1100 Pump, while in the second part AIM project is described. In addition to in vivo and in silico analyses, in vitro experiments are becoming increasingly important, since they allow to perform measurements that can not be implemented in vivo because of their invasivity. Several in vitro set-ups have been developed, to simulate both physiological or pathological human blood circulation, by varying loop parameters. They also allow to directly examine the behaviour of cardiovascular devices before their implant in patient’s body, such as prosthetic valves and stents, and they constitute an important tool for surgeon’s training.