Recently, the ecosystem perspective has offered a novel way to analyze technological diffusion and competition, which has been extensively leveraged to understand born-digital firms. These, however, represent only a part of the competitive landscape. Non-born-digital industries, like those focusing on manufacturing, have traditionally been arranged in a network composed by peripheral and core firms, with the latter characterized by holding superior knowledge and the control over the network. Yet, the “digital transformation” of non-born-digital firms is scarcely investigated, and we have limited understanding on how this process may shift the firms’ position in the knowledge and supply network, thus affecting the entire ecosystem.