The present study primarily focuses on the investigation of EGFR-positive tumors, characterized by uncontrolled proliferation and increased growth, as observed in malignancies such as breast cancer and melanoma. Breast cancer is stated to be the most prevalent cancer among women globally, characterized by its biological diversity in terms of molecular subtypes such as luminal A/B, HER2-positive and triple negative. These subtypes have different epidemiological risk factors, different natural histories, and different responses to treatments1. The continuing decrease in mortality from breast cancer has been attributed to early detection due to screening, improved adjuvant therapy, and more recently to decreases in the incidence due to lowered rates of usage of hormone replacement therapy.