The fast growth rate in plastic waste and the rising need for sustainable road construction have caused searching for new innovative approaches, such as the integration of recycled plastics and RAP into asphalt mixtures. Plastic waste disposal poses a global challenge due to low recycling rates and high landfilling costs. However, incorporating waste plastics into asphalts offers a circular economy solution, leading to both environmental benefits and enhanced pavement durability according several studies. Likewise, RAP has gained significant attraction due to being a cost-effective and eco-friendly alternative to virgin aggregates and bitumen. This thesis aims to characterize and compare the fatigue behaviour of sustainable asphalt mixtures incorporating 50% RAP and various percentages of recycled plastics.