In an era characterized by rapid technological advances and global interconnectedness, the landscape of innovation and entrepreneurship has undergone significant transformations. In my thesis I explored several chapters that provide an overview of the relationship between innovation and startups and then explore the figure of the entrepreneur of innovative startups coming from two different geographical areas with which I came into contact during my academic career: Italy and Netherlands. Chapter 1 delves into the fundamental aspects of innovation and startups, laying the foundations for a comprehensive exploration of the complex dynamics that govern entrepreneurial initiatives. The chapter provides a meticulous definition of innovation, revealing its multifaceted nature and highlighting its central role in driving economic growth and social progress.