This thesis faces the application of LEED protocol into two different case studios: one is made up of two buildings used as Students Residences located in Torino, while the second is an Industrial Warehouse located in Mantova. The thesis represents one of the most actual themes, for relevance, since the LEED protocol is an instrument to design and actuate measures to improve sustainability in buildings. Sustainability that has becoming relevant in construction sector, due to its negative impact on climate changes (that can led to dangerous consequences for human’s life on earth). The work follows, also, the principles of Sustainable Development Goals, where some of the target to be reached by 2030 are considered in credits of the protocol.