Dopamine is a type of neurotransmitter and hormone. It plays a role in many important body functions, including movement, memory, pleasurable reward, and motivation. High or low dopamine levels are associated with several mental health and neurological disorders. With these diseases on the rise, it is imperative to improve our understanding of the basics of neuronal transmission. Limitations in the selectivity and sensitivity hinder most biosensor platforms from detecting physiologically relevant changes in neurotransmitter concentrations in real-time. Moreover, spatial resolution nearing synaptic ranges 20-40 nanometers (nm) stays challenging for most of the state-of-the-art techniques. Dopamine-specific nanopipette sensor claim to bea promising candidate for serving these issues.