The paper examines the Computational Fluid Dynamics analysis of a bus air conditioning system. The bus under examination has a capacity of 29 sitting and 25 standing passengers. The effectiveness and efficiency of the system were analyzed through the Anasys Fluent software. During the study, the experimental results were put in comparison with the outcome of CFD results. For clarity of CFD results and to reach a significantly close outcome, different error elimination techniques, such as Mesh error elimination, were applied for the betterment of the work. Besides, to be precise, two different turbulence models, k-ϵ Standart and k-ω SST models were applied to the indicated system for deduction of a suitable method.