The work set its basis on the European project Waste2Watts, that aims to design and build a large-scale biogas fuelled SOFC power plant. The biogas is supposed to be produced in a large farm and it consists mainly of methane and carbon dioxide. However, in order to guarantee the long-term correct operation of the SOFC, the biogas needs to be desulphurized and cleaned of other contaminants, like mercaptans e siloxanes. Here is where the efforts are put: the idea is to adopt a cryogenic cleaning system without use of chemicals or biological agents, in order to make the contaminants to condense and be suitably removed.