Global warming is an important worldwide problem and the CO2 emissions are one of the main concerns. The use of CO2 as raw material for value added products has not already an important relevance; the small quantity used so far is mainly converted in carbonates and urea. It can be understood since carbon dioxide is a very stable molecule. Catalysts are being investigated to reduce the energy required to transform it to more complex molecules. Electrochemical reactions let to achieve transportation fuels, also have good controllability, efficiency and scalability, but in general have a low selectivity. In contrast, the most remarkable benefits of the use of biocatalysts, in addition to be environmentally friendly, are their high selectivity and specificity, but are more difficult to control, less flexible with the change of conditions and very instable.