The work done of this thesis is inserted within a research activity very broad and interdisciplinary which figures out the refinery’s potential risks, among possible external events, attention has been paid to the seismic event. The aim of this study is based on the “potential dangers of petrochemical plants affected by seismic activity”, according to the damage caused by the Kocaeli earthquake to the Tupras Izmit petrochemical plant, the potential hazards of the earthquake to the petrochemical plant are summarized.