Silvia Cortese
Analysis of Heat Transfer in Biological Tissue Using the Finite Difference Method.
Rel. Guido Perrone, Alberto Vallan, Aurora Bellone. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Energetica E Nucleare, 2025
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Abstract
Cancer remains one of the main causes of death worldwide. Conventional treatments such as surgery, chemotherapy, and radiotherapy are widely employed, but often have significant side effects and limitations, highlighting the need for new and less invasive therapies. Among emerging approaches, Laser Ablation is a promising thermal therapy that induces controlled heating of the targeted tumor tissue, offering high precision and minimal invasive impact. Optimized treatments require accurate control of the temperature, which is still a challenge. A proposed solution is to use fiber optic sensors, particularly FBG sensors, to measure temperature in real time. However, further research is still required to develop a reliable method for reconstructing the temperature distribution in the entire tumor mass.
This master’s thesis aims to analyze the thermal evolution in a biological tissue, developing a model designed to reproduce the resulting temperature distribution evolution following a laser heat pulse within the tissue, offering valuable insights into how thermal energy propagates and accumulates during treatment
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