This thesis, developed in collaboration with Toyota Motor Europe, presents the studies conducted on innovative materials to decrease the content of iridium in anode catalyst used for PEM water electrolysis. This study delves into an extensive literature review, aiming to identify new morphologies and chemistry that could meet the requirements. Although PEM water electrolysis is a promising technology for green hydrogen production, its reliance on scarce and costly iridium motivates the search for alternative catalysts with lower noble metal content. The objective of this work was to investigate the electrochemical performance of three different class of low-iridium catalysts, each characterized by distinct chemistry, morphology and synthesis methods.