Cell culturing and in vitro testing are the cornerstone investigations that allowed the development of medicine and biology in the last century. Nevertheless, the most of studies requires a series of operations that involve manual handling of liquid substances through pipetting devices. Those, in addition to being highly time-consuming, are accompanied by the possibility of errors related to the manual dexterity and experience of the operator. Therefore, it clearly emerged the necessity to develop smart biomedical devices that may help end-users to save time and enable more controlled procedure. Automatic pipetting helped to face this problem, but on the other hand the complexity of in-vitro studies still request considerable human efforts.