The advancement of technology has drastically changed the way of interaction between human and vehicles. Considering the steering wheel, until now, cars vendors have started to include more buttons on it to control many functions, such as phone answering, infotainment and Advanced Driver Assistance Systems (ADAS) management and so on. An innovative concept of a multi-sensors steering wheel has been developed in recent years. It includes sensors that can acquire driver physiological data, obtained through various parameters such as electrodermal activity, heart rate variability and so on. The multi-sensor steering wheel could improve the overall driving experience, e.g. helping to integrate functions in the ADAS to prevent accidents by alerting the driver to potential hazards, detecting the driver's physical condition, improving the comfort of the driver and so on and so forth.