The transport sector is one of the sectors that contribute most to CO2 and greenhouse gases emissions, contributing to climate change that leads to serious hardship in the word. Nowadays, the transport sector, in particular the heavy transport sector which the report focuses, is mainly made up of conventional trucks, that is, Diesel-powered. The goal si to progressively replace these vehicles with trucks powered by zero-impact sources on the environment, such as hydrogen and electricity that can be produced through renewable sources and therefore without the emission of CO2 into the environment (or with minimum quantities). In order to study the feasibility of this operation and to better understand when this transition from conventional trucks to alternative trucks can be done, the elaborate develops a new model for the estimation of the Total Cost of Ownership (TCO).