Severe vision impairment and blindness represent one of the major medical challenges of the next decades, especially in western countries due to the population ageing. Today, the World Health Organization estimates that at least one billion people worldwide suffer from moderate or severe distance vision impairment or blindness due to unaddressed refractive error (88.4 million), cataract (94 million), age-related macular degeneration (8 million), glaucoma (7.7 million) and diabetic retinopathy (3.9 million). This numbers are expected to worsen considering that the prevalence of severe impairment leading to blindness is larger in over 50-year-old people. The social impact of such diseases is very high because it limits working capacities and, in the case of elder adults, contributes to social isolation, difficulty in walking, with the consequence of higher risk of falls and fractures.