Brain injuries represent a relevant current public health problem. Often, they lead to periods of unconsciousness, coma, or even death. Generally, individuals who exit from a period of coma survive in a non-responsive state, unable to voluntarily respond to external stimuli. For these nonresponsive patients, even though they accomplish movements, it is not trivial to establish and associate them with a level of consciousness, in order to interpret their intentions. This obstacle may easily conduct to misleading diagnoses. In order to obtain a more reliable diagnosis, it is essential to establish and develop methods able to enhance studies of various levels of consciousness in nonresponsive patients.