Lithium-ion batteries are representing nowadays the reference technology for the state-of-the-art energy storage system in hybrid and electric vehicles. Countless are the parameters to take into account for an optimal battery operation, from physical and chemical point of view, in addition to all the charging and discharging phases concerning the battery life and how it can be managed. A proper and accurate State of Health (SOH) prediction is needed to take right countermeasures and precautions defining a control strategy aimed to correctly exploit HV-Batteries along its whole life and extending it as well. From the customer point of view, having the proper idea of whenever the battery would be replaced is really important advantage that comes out from a proper SOH prediction.