Covid-19 has deeply modified the industrial environment: spaces have been re-thought, and relationship among people has changed, with the introduction of smart working and social distance protocols. One of the most important aspect big companies have to face in this particular historical moment is the reduction of losses and waste, focusing on costs reduction and profits increase. Furthermore, with the pandemic situation, an inexplicable increase in market demand has been registered, forcing companies to redesign their production systems. In this scenario, the application of the World Class Manufacturing methodology is fundamental to analyse the current state of the processes, the main causes of losses, and to decide the improvement actions to be performed.