CubeSats are increasing their importance in the Space Market. Introduced as educational platforms, they are now spreading in the industrial context. Given their reduced complexity, CubeSat platforms are characterized by a development time which is reduced by several factors with reference to “traditional” Space Missions. It would not be possible, in this context, to develop Space Segment and Ground Segment independently: one of the major implications is the fact that pre-flight tests are used both for Space Platform and Ground Systems validation. The philosophy is to ensure the real Ground Systems are connected with spacecraft hardware as soon as possible. The main purpose of this thesis is that of presenting an example of Ground Segment Software Architecture in the frame of Small Satellite Operations.