Telepathology refers to practicing pathology from a distance. Telecommunications technology is used for facilitating the transmission of pathology image-rich data between two distant locations for diagnosis, research and education purposes. In order to perform telepathology, a pathologist must choose the video images that need to be analyzed and then render a diagnosis. The use of television microscopy, which preceded telepathology, didn’t require a pathologist to have a virtual or physical hands-on involvement in choosing the microscopic fields-of-view to analyze and diagnose. Today, With the wide application of prediction, especially in the telemedicine field, the research of prediction algorithm and theory has made a great progress.