The paper proposes the analysis of the potential of a hybrid plant, based on renewable sources and coupled to a storage system, for the Greek islands not interconnected to the national electricity grid. The goal is to demonstrate that the plant is able to satisfy the energy load of these islands, making them independent from the purchase and subsequent use of fossil fuels for a whole year. Initially, all the islands in Greece that could be interesting for being covered only by RES through the application of power to power storage systems will be identified and divided into load groups. Once the case studies have been selected, their energy producibility and relative consumption will be studied; data that will be processed through an optimization algorithm to obtain the optimal system configurations in different cases.