Tongue is an organ located in the oral cavity that plays a fundamental role in numerous activities such as mastication, swallowing, breathing and speech. It is composed almost entirely of muscle tissue, but despite the relevance of its function, its electro-muscular activity is still poorly analysed and understood. Currently, electrophysiological studies of the tongue are performed with needle electromyography, which represents a limitation both in terms of applicability and capability to extract information at the global muscle level. Due to its functions, requiring a wide range of fine movements, tongue is widely represented at cortical level, therefore, several traumatic events or pathologies involving the central nervous system may impair its function.