One of the most critical subsystems in vehicles are suspensions because they are subjected to high transient loads in different directions. The development of a methodology to asses suspension components durability requires a mixture of different background knowledge, for instance, vehicle dynamics, fatigue, fem analysis, mathematical statistics together with practical experience in industry field. For this reason, it is the result of a collaboration with different departments in AVL List GmbH. The interdepartmental collaboration drew on the need to reduce the duration and the cost of vehicle developments but ensuring the same level of reliability and robustness. To accomplish this task, it’s no more enough to assume a high level of static safety factor and then testing durability when a prototype will be available.