Nowadays vehicles are embedding more complex functionalities, reason for which, the demand of Electronic Control Units able to perform safety-relevant tasks is increased. It leads the automotive industry to find novel verification and validation methodologies act to improve the quality of the assessment. The ISO26262:2018 automotive functional safety standard requires to follows a strict development process, compliant with its “safety lifecycle”. It provides a guideline for all the phases of the item life, in particular for the hardware/software integration validation, since usually the software is in charge to mitigate the effects of some possible hardware failures. This thesis proposes a novel technique to aid the designers to perform the Failure Mode, Effect, and Diagnostic Analysis of hardware designs.