Dental infections are very common and become dangerous if underestimated. In endodontal operations, the vitality of the tooth is often lost as the root cannot remain exposed to infections, there is a risk of bacteria spreading throughout the body. Currently, the treatments include the use of disinfectant irrigates, which are cytotoxic in the effective bactericidal concentrations. In recent years, more and more conservative approaches have been sought that allow a real regeneration of the tooth (regenerative endodontics). Several nanomedicine platforms are being explored for their ability to interact with pathogens and, at the same time, are safe for cells. The aim of this project is the development of a multifunctional platform capable of eliminating and preventing infections and, at the same time, stimulating the reconstruction of the pulp chamber.