Human relations are part of our everyday. They manifest in a plurality of forms, movements, institutions and spaces. Thus if they have a reality, they can be studied as such. This thesis explores the so-called “design of relation”, arguing that in certain contexts - such as that of metropolitan cities in countries with evolved economies - the most intense forms of social interaction are exchanged within opaque contexts, where different social categories can find their own niches or insides to gather. In this framework, specific relational phenomenons can be related to as spatial local thoughts, perceived as objects that could be extracted from their own contexts, broken down and re-assembled basing on different conditions and according to other spatial local thoughts.