Cardiovascular diseases are a major cause of death , due to the rising incidence of obesity and diabetes in the Western world. Atherosclerosis is a vascular pathology where the accumulation of fat inside the arterial wall involves the formation of lipidic plaques, causing the narrowing or block of arteries. These plaques are usually located in the coronary arteries and atherosclerosis is in fact the main cause of coronary artery disease. The etiological factors of atherosclerosis have not been fully elucidated yet. However, it is well-known that hemodynamics plays an important role in the local onset and progression of vascular disease. This “hemodynamic hypothesis” suggests a co-localization of lesion prevalence at geometrically predisposed districts, such as arterial bifurcations, and disturbed flow regions, usually characterized by low and oscillatory wall shear stress (WSS).