The somatosensory system detects changes in the surrounding environment through the five sensory modalities. Somatosensory evoked potentials (SEPs) are electrical signals elicited by the ascending sensory pathways in response to peripheral nerve stimulation. SEPs can be triggered by different sensory stimuli, such as pain, touch, vibration, or mechanical devices, which stimulate specific sensory receptors and elicit modality-specific SEPs. Stimulation of the median or ulnar nerve of the wrist is used to elicit SEPs related to the upper limb, while the SEP of the lower limb is elicited by stimulating the tibial nerve of the ankle or the peroneal nerve at the popliteal fossa.