In the field of osteosynthesis, modelling of medical devices in silico is essential to predict and simulate their post-implantation behavior. The purpose of these procedures is to develop and facilitate an increasingly patient-specific approach that prevents the occurrence of complications due to errors in the placement of the implant. The term osteosynthesis refers to a reconstructive surgical technique whose purpose is to join two or more bone fragments after their realignment, using screws, plates and other devices, involving materials with both mechanical and biological properties appropriate to the implant. In this regard, it is of utmost importance to adopt a patient-specific approach, as implant failure or success depends on both technical choices and patient-related factors.